Place the beef into a 6 quart slow cooker. Sprinkle the beef roast evenly with the salt, thyme, garlic powder, onion powder and pepper.
Cook on LOW power for 8 - 10 hours. Shred the meat, being sure to discard any visible fat. Portion the meat into four separate containers (about 3/4 - 1 pound each) for meals.
Shredded beef can be stored in air-tight containers for up to one week in the refrigerator or up to one month in the freezer.